Cannabis for Post-Traumatic Stress Disorder: A Neurobiological Approach to Treatment

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The endocannabinoid system is intricately involved in regulation of the neurobiological processes, which underlie the symptomatology of posttraumatic stress disorder (PTSD).

This article discusses the neurobiological underpinnings of PTSD and the use of cannabis for treating PTSD in the New Mexico Medical Cannabis Program.1

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Four Types of Cannabinoid Receptors For Killing Pain and Stopping Inflammation

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Cannabinoids interact with different cannabinoid receptors in the body, sometimes in tandem and sometimes in competition. Each activation gives a response to dampen pain stimuli and reduce inflammation.

The most well known cannabinoid receptors, CB1 and CB2, are proteins that are imbedded in the membrane of cells. These surface proteins are then attached to another protein that determines the signaling direction: activation or inhibition. The signal that goes out will depend on which molecule (THC, for example, will activate) that binds to the receptor. There are, however, many other receptors in the human body that are activated by cannabinoids.

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